2025 March Madness Odds: Duke Opens as Favorite Over UConn for 2024-25 NCAA Tournament

The 2025 March Madness odds are already available across our best March Madness betting sites with Duke opening as the betting favorite after UConn's back-to-back titles.

Duke is the early betting favorite by the 2025 March Madness odds with odds as low as +1000 representing an implied win probability of 9.09%. UConn - the reigning back-to-back NCAA Tournament champion - and North Carolina come up close behind.

The 2025 Final Four and NCAA Tournament championship game will be played at the Alamodome in San Antonio, Texas on April 5 and 7.

To help with your 2025 March Madness predictions, here's a look at the early March Madness odds and our best college basketball picks to help with your March Madness predictions.

March Madness odds 2025

(Odds updated April 9)

After FanDuel was the first of our best sports betting sites to release odds for March Madness in 2025, DraftKings followed suit ahead of Monday's title game. And the top of the board shouldn't surprise anyone.

Duke opened as the favorite across the first two of our best sportsbooks to hang this market, with odds as short as +1000 at DraftKings. With No. 1 recruit Cooper Flagg headlining the top recruiting class in the country, Jon Scheyer's group will have its sights set higher than its Elite Eight finish in 2024.

UConn is tied for the second-shortest odds at DraftKings, joining fellow blue bloods North Carolina and Kansas, while the Huskies are dealing as high as +1500 at FanDuel behind those other two schools. Houston, Arizona, Alabama, and Baylor are the only schools with shorter than 20/1 odds at either shop.

Even after this year's run to the title game, Purdue is dealing between +2800 and +3000 in the early odds for 2025. While Edey technically has another year of eligibility, he's already said this is his last season, and it'll be tough for the Boilermakers to replace the 7-foot-4 star center.

Where can I bet on March Madness?

March Madness odds are available in all legal and regulated U.S. sports betting states and at all of our best March Madness betting sites. Note that some stats will prohibit bettors from wagering on schools within that state. Others don't allow users to wager on player props for college sports.

Be sure to always check with your state's regulations.

What is March Madness?

March Madness captivates sports fans across the nation with its intense competition and electrifying atmosphere. This annual event, organized by the NCAA, features a single-elimination tournament that pits 68 of the best college basketball teams against each other in a quest for championship glory. The tournament unfolds over several weeks in March and April, culminating in the crowning of the NCAA Men's Basketball Champion.

What sets March Madness apart is its unpredictability and penchant for producing thrilling upsets and Cinderella stories. Teams from all corners of the country, representing a diverse array of conferences and backgrounds, converge on the court with dreams of cutting down the nets as champions.

From buzzer-beaters to nail-biting finishes, March Madness delivers unforgettable moments that captivate audiences and leave a lasting imprint on the annals of college basketball history.

March Madness odds explained

March Madness odds are a futures market with the odds for the next season's champion being released shortly before or after the conclusion of the current year's NCAA Tournament. In fact, 2025 March Madness odds have already been released at some sportsbooks, with more expected to come after Monday's title game.

The odds are then routinely adjusted over the course of that year. Coach hirings and firings impact the odds, as do player transfers and injuries. Once the regular season begins, player and team performance is reflected in the odds.

The better a team performs, the shorter its odds will become. For example, if North Carolina were to open at +2000 in a given year but then started 10-0, its odds would likely shorten to +1500. If the Tar Heels opened at +2000 but then started 0-10, their odds would likely lengthen to +5000 or higher. The lower the odds, the higher that team's implied probability of being the eventual winner in the futures market.

How to bet college basketball futures

To maximize your betting experience during March Madness, it's essential to adopt a strategic approach. Begin by immersing yourself in the intricate world of college basketball, meticulously analyzing each team's performance throughout the regular season and conference tournaments.

Once you've thoroughly researched the teams and assessed their strengths and weaknesses, it's time to explore the multitude of betting options available. From traditional moneyline bets to more exotic prop bets, sportsbooks offer a diverse array of wagering opportunities for March Madness enthusiasts. Consider placing bets on individual game outcomes, point spreads, or even futures bets on the tournament champion or March Madness MVP odds.

Past March Madness winners

March Madness FAQs

Who is the March Madness 2025 favorite?

The Duke Blue Devils are the opening favorites to win the 2025 NCAA Tournament, with odds ranging from +1000 to +1200. Those odds imply a win probability between 7.69% and 9.09%.

Who won March Madness last year?

UConn defeated the Purdue 75-60 to win the 2024 NCAA Tournament. That marked back-to-back victories for the Huskies.

When will March Madness be decided?

The 2025 national championship game will take place on Monday, April 7.

Where will March Madness be played?

The Final Four of the 2025 NCAA Tournament will be played at the Alamodome in San Antonio.

March Madness betting odds pages

Here are our best March Madness betting sites:

• Caesars Promo Code: SBRBONUS1000 | Read our Caesars Review
• BetMGM Bonus Code: SBRBONUS | Read our BetMGM Review
• bet365 Bonus Code: SBRBONUS | Read our bet365 Review
• BetRivers Promo Code: SBRBONUS | Read our BetRivers Review
• FanDuel Promo Code | Read our FanDuel Review
• DraftKings Promo Code | Read our DraftKings Review

(21+. Gambling Problem? Call 1-800-GAMBLER)
* Bonuses not applicable in Ontario.

Related pages

• Best Sports Betting Sites | Best Sportsbook Promos (U.S. only)