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Ohio State Buckeyes head coach Ryan Day celebrates during the game as we make our Ohio State vs. Notre Dame early picks and odds ahead of the CFP National Championship.
Pictured: Ohio State Buckeyes head coach Ryan Day celebrates during the game. Photo by Jerome Miron-Imagn Images.

The inaugural 12-team College Football Playoff comes to a close Monday evening when the Ohio State Buckeyes square off against the Notre Dame Fighting Irish. Kickoff is slated for 7:30 p.m. ET (ESPN) from Mercedes-Benz Stadium in Atlanta.

Our Ohio State vs. Notre Dame early picks and odds break down the best markets ahead of the College Football National Championship Game, with a focus on the favorites. Our best college football betting sites list the Buckeyes as 8.5-point favorites with a total of 46.5 by the Ohio State vs. Notre Dame odds.

My early Ohio State vs. Notre Dame prediction: CFP National Championship

College football picks made Friday; odds subject to change. Our NEW college football player prop odds tool can help you find the best odds on any market across legal sportsbooks in your area!

Prediction: Ohio State -8

Best odds: -110 via Caesars | Implied probability: 52.38%

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Since losing to Michigan in the last week of the regular season, Ohio State hasn't put a foot wrong. The Buckeyes have beaten the No. 1, No. 3, and No. 7 teams in the country by an average of nearly 20 points per game. Ryan Day has his team firing on all cylinders right now.

Furthermore, the national championship hasn't been decided by one score since 2018. The average winning margin during that span is 28 points, with Clemson, LSU, Alabama, Georgia (twice), and Michigan all winning by at least 15 points.

If Notre Dame finds itself down by double digits against the nation's top scoring defense, it doesn't have any explosive threats in the passing game to lean on. The Fighting Irish don't have a single player who tallied 500 receiving yards, and Riley Leonard hasn't particularly stood out with his passing numbers.

At the end of the day, we're backing Ohio State to continue to take care of business. Our best sports betting sites list the Buckeyes at standard juice to cover an 8-point spread.

Don't miss our guide for how to bet on college football or this week's best sportsbook promos.

Ohio State vs. Notre Dame live odds

See the college football odds from our best college football betting sites for every college football bowl game.

Moneyline

As kickoff nears, Ohio State's moneyline odds have continued to creep toward a more favorable number for Buckeyes backers. They were hovering around -400 earlier in the week, but BetMGM now offers the best line at -350. Notre Dame continues to be a profitable moneyline play as a significant underdog of 3/1.

Spread

  • Ohio State best odds: -8 (-110) via Caesars
  • Notre Dame best odds: +9.5 (-112) via BetRivers

Bettors have overwhelmingly backed Ohio State in the build-up to the national championship. However, in this industry, lines must be drawn in the sand. When our best sportsbooks made the Buckeyes 9.5-point favorites, public money poured in on Notre Dame, which saw the spread crawl back to -8 or -8.5.

Over/Under

There hasn't been much movement in the total market during the week leading up to the College Football Playoff's pinnacle. The most significant change is Caesars jumping from a total of 45.5 to O/U 46. The -105 odds at the sportsbook indicate a potential movement back to 45.5 over the weekend, which is good news for those with an eye on the Over.

Ohio State vs. Notre Dame odds movement

Ohio State vs. Notre Dame expert picks: CFP National Championship

Along with our Ohio State vs. Notre Dame expert picks, we've broken down this matchup from every angle - including full team previews for Ohio State and Notre Dame and how they compare in key areas ahead of Monday's CFP National Championship Game.  

How to watch the CFP National Championship

  • When: Monday, Jan. 20
  • Kickoff: 7:30 p.m. ET
  • Where: Mercedes-Benz Stadium (Atlanta)
  • How to watch: ESPN/ESPN+
  • Weather: Indoors
  • Favorite: Ohio State -8.5 (-110 via BetMGM)

College football betting odds pages

Here are our best college football betting sites:

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