College Football Week 13 Predictions: Picks & Odds for Marquee Games

Rob Paul

Last Updated: November 19, 2024 8:09 PM EST • 3 min 57 sec read. Twitter link Google News Link

Northwestern defensive back Damon Walters tries to tackle Ohio State wide receiver Jeremiah Smith. The Buckeyes' game with Indiana is the biggest matchup of our Week 13 college football predictions. — Northwestern defensive back Damon Walters tries to tackle Ohio State wide receiver Jeremiah Smith. Photo by David Banks via Imagn Images.

In the second last week before conference championships, our Week 13 college football predictions look at the most important matchups.

College football championship odds favorite Ohio State takes on Indiana and its Cinderella story in a game that will impact the Big Ten Championship
Led by Heisman Trophy odds favorite Travis Hunter, Colorado faces a must win game against Kansas to keep its College Football Playoff hopes alive
As Army makes a push to be the Group of Five College Football Playoff odds leader, the Black Knights look to spoil Notre Dame's CFP hopes

While Week 13 lacks for AP Top 25 matchups, there's several marquee teams that need to win if they want to play meaningful football in late December.

College football picks & predictions Week 13

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Buffalo vs. Eastern Michigan prediction
Ohio vs. Toledo prediction
NC State vs. Georgia Tech prediction

NC State vs. Georgia Tech player props

Temple vs. UTSA prediction
Purdue vs. Michigan State prediction

Purdue vs. Michigan State player props

UNLV vs. San Jose State prediction
Indiana vs. Ohio State early picks

Indiana vs. Ohio State prediction
Indiana vs. Ohio State player props

Ole Miss vs. Florida prediction
Kentucky vs. Texas prediction

Kentucky vs. Texas player props

Colorado vs. Kansas prediction

Colorado vs. Kansas player props

Army vs. Notre Dame prediction
Alabama vs. Oklahoma prediction

Don't miss the rest of our Week 13 college football picks.

College football odds for Wednesday

College football odds via DraftKings and subject to change. Follow the latest college football scores for line history and matchup info.

Buffalo vs. Eastern Michigan odds

Prediction: Eastern Michigan -1 (-112 via DraftKings)⭐⭐⭐

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Pick made by Mike Spector.

When: Wednesday, Nov. 20 (7 p.m. ET)
Where: Rynearson Stadium (Ypsilanti, Mich.)
How to watch: ESPN2
Moneyline: Buffalo (+110) | Eastern Michigan (-130)
Spread: Buffalo +2.5 (-108) | Eastern Michigan -2.5 (-112)
Total: 53.5 (-110/-110)

Ohio vs. Toledo odds

Prediction: Under 44.5 (-105 via FanDuel) ⭐⭐⭐⭐⭐

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Pick made by Brenden Schaeffer

When: Wednesday, Nov. 20 (7 p.m. ET)
Where: Glass Bowl (Toledo, Ohio)
How to watch: ESPN
Moneyline: Ohio (+105) | Toledo (-125)
Spread: Ohio +2.5 (-110) | Toledo -2.5 (-110)
Total: 44.5 (-108/-112)

College football odds for Thursday

NC State vs. Georgia Tech odds

Georgia Tech running back Jamal Haynes reacts after scoring a touchdown against Miami. Georgia Tech is part of our Week 13 college football predictions. — Georgia Tech running back Jamal Haynes reacts after scoring a touchdown against Miami. Photo by Brett Davis via Imagn Images.

Prediction: Haynes King Over 204.5 passing yards (-114 via FanDuel) ⭐⭐⭐⭐

Pick made by Phil Wood

When: Thursday, Nov. 21 (7:30 p.m. ET)
Where: Bobby Dodd Stadium (Atlanta, Ga.)
How to watch: ESPN
Moneyline: NC State (+250) | Georgia Tech (-310)
Spread: NC State +9 (-110) | Georgia Tech -9 (-110)
Total: 52.5 (-110/-110)

College football odds for Friday

Temple vs. UTSA odds

When: Friday, Nov. 22 (7 p.m. ET)
Where: Alamodome (San Antonio,Texas)
How to watch: ESPN2
Moneyline: Temple (+525) | UTSA (-750)
Spread: Temple +16.5 (-112) | UTSA -16.5 (-108)
Total: 56 (-110/-110)

Purdue vs. Michigan State odds

When: Friday, Nov. 22 (8 p.m. ET)
Where: Spartan Stadium (East Lansing, Mich.)
How to watch: FOX
Moneyline: Purdue (+400) | Michigan State (-535)
Spread: Purdue +13.5 (-108) | Michigan State -13.5 (-112)
Total: 48 (-110/-110)

UNLV vs. San Jose State odds

When: Friday, Nov. 22 (10 p.m. ET)
Where: CEFCU Stadium (San Jose, Calif.)
How to watch: FS1
Moneyline: UNLV (-285) | San Jose State (+230)
Spread: UNLV -7.5 (-108) | San Jose State +7.5 (-112)
Total: 62 (-110/-110)

College football odds for Saturday

Indiana vs. Ohio State odds

When: Saturday, Nov. 23 (noon ET)
Where: Ohio Stadium (Columbus, Ohio)
How to watch: FOX
Moneyline: Indiana (+350) | Ohio State (-455)
Spread: Indiana +12.5 (-108) | Ohio State -12.5 (-112)
Total: 52 (-112/-108)

Ole Miss vs. Florida odds

When: Saturday, Nov. 23 (noon ET)
Where: Ben Hill Griffin Stadium (Gainesville, Fla.)
How to watch: ABC
Moneyline: Ole Miss (-360) | Florida (+285)
Spread: Ole Miss -10 (-112) | Florida +10 (-108)
Total: 55.5 (-108/-112)

Kentucky vs. Texas odds

When: Saturday, Nov. 23 (3:30 p.m. ET)
Where: DKR-Texas Memorial Stadium (Austin, Texas)
How to watch: ABC
Moneyline: Kentucky (+900) | Texas (-1600)
Spread: Kentucky +20.5 (-110) | Texas -20.5 (-110)
Total: 47 (-112/-108)

Colorado vs. Kansas odds

When: Saturday, Nov. 23 (3:30 p.m. ET)
Where: Arrowhead Stadium (Kanas City, Mo.)
How to watch: FOX
Moneyline: Colorado (-148) | Kansas (+124)
Spread: Colorado -3 (-108) | Kansas +3 (-112)
Total: 59.5 (-110/-110)

Army vs. Notre Dame odds

Army quarterback Bryson Daily carries the ball against North Texas. Army is part of our Week 13 college football predictions. — Army quarterback Bryson Daily carries the ball against North Texas. Photo by Danny Wild via Imagn Images.

When: Saturday, Nov. 23 (7 p.m. ET)
Where: Yankee Stadium (Bronx, N.Y.)
How to watch: NBC, Peacock
Moneyline: Army (+425) | Notre Dame (-575)
Spread: Army +14 (-108) | Notre Dame -14 (-112)
Total: 44.5 (-112/-108)

Alabama vs. Oklahoma odds

When: Saturday, Nov. 23 (7:30 p.m. ET)
Where: Memorial Stadium (Norman, Okla.)
How to watch: ABC
Moneyline: Alabama (-550) | Oklahoma (+410)
Spread: Alabama -14 (-108) | Oklahoma +14 (-112)
Total: 47.5 (-108/-112)

College football picks roundup: Week 13

College football Week 13 ATS picks
College football Week 13 upset picks
College football Week 13 player props
College football Week 13 expert picks

College football betting odds pages

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Written By:
Rob Paul

Rob is a Publishing Editor at Sportsbook Review. He’s been with the team since early 2024, with this being his first full-time role in the sports betting industry. Before joining SportsbookReview.com, he contributed to various sports outlets, including FanSided and Pro Football Network. During that period, he spent five years working full-time as a local community journalist, after attending Durham College for journalism and Wilfrid Laurier University for history. He previously hosted an NFL draft and college football-focused podcast where he had the opportunity to interact with future NFL players such as Maxx Crosby and Quinn Meinerz. Rob has spent multiple years working as a freelance podcast producer for numerous sports-related podcasts while making guest appearances on several college football shows. He’s also made guest appearances on SportsTalk Mississippi on several occasions to talk all things NFL draft. Rob values the way sports betting acts as a catalyst for telling stories and growing interest in certain sports, particularly FCS football, WNBA, and mid-major college basketball. He’s always been drawn to the more obscure teams and conferences in major college sports, but most of all, Rob loves using stats to find the best player props to back.